Figure 4.

Percentage of circulating platelets expressing PAC-1, P-selectin, CXCL16, and CXCR6 from active and not active smoking chronic obstructive pulmonary disease (COPD) patients and aged-matched controls by flow cytometry. Platelets were stained with conjugated antibodies against (A) CD41 and PAC-1, (B) CD41 and P-selectin, (C) CD41 and CXCL16, and (D) CD41 and CXCR6. Results are expressed as percentage of positive cells (n = 15 aged-matched controls, n = 17 active smokers COPD patients, n = 16 ex-smokers COPD patients). Values are expressed as mean ± SEM. *P < 0.05 or **P < 0.01 relative to values in the control group.