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. 2017 Oct 26;292(50):20644–20654. doi: 10.1074/jbc.M117.818476

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© 2017 by The American Society for Biochemistry and Molecular Biology, Inc.

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Figure 7. — DHPG potentiates synaptic glutamate release through NMDARs in the spinal dorsal horn. A and B, representative recording traces and cumulative plots (A) and box-and-whisker plots (B) show no effect from application of 20 μm DHPG on the frequency and amplitude of mEPSCs of lamina II neurons from vehicle-treated rats' spinal cord slices incubated with 50 μm AP5 (n = 8 neurons, 4 rats). C and D, original recording traces and cumulative plots (C) and box-and-whisker plots (D) show no effect from application of 20 μm DHPG on the frequency or amplitude of mEPSCs of lamina II neurons from paclitaxel-treated rats' spinal cord slices incubated with 50 μm AP5 (n = 8 neurons, 4 rats). Box-and-whisker plots show medians, 25th, and 75th percentiles, and ranges.