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TRPC1 KO mice fed a HF diet and exercised have fewer adipocytes. Adipose tissue harvested from WT and TRPC1 KO mice following 12 weeks of diet and exercise was measured by a Multisizer. Data are presented as mean ± S.D., n = 6–8. Significant (p < 0.05) effects from 3-way ANOVA are indicated by + (mouse type), × (diet), and # (exercise). A significant interaction was further analyzed using post hoc Tukey to perform pairwise comparisons. *, p < 0.05; **, p < 0.01.
