Fig. 6.
Live labeling with sema4D antibody shows change of outer retina sema4D in WT and RCS retina comparing after light onset. a Live sema4D antibody and secondary antibody labeling (shown in red) of whole mount WT retina 1 hour before and after light onset as indicated. b Quantification of signal intensity of images as in a. c Labeling of RCS rat retina as in a. d Quantification of signal intensity of images as in c. Images show representative maximal projections of x-y confocal image stacks obtained in three independent experiments. Scale bars: 10 μm. Bars show mean ± SD of three independent experiments with duplicate samples each. Asterisks indicate significant difference of sema4D levels before and after light onset, p < 0.05 by Student’s t-test.