Table 2.
Histopathological parameters in study groups
| Parameter | Total | TMA | Non-TMA | P value | |
|---|---|---|---|---|---|
| Class | II | 8 (4.1%) | 1 (2%) | 7 (4.8%) | |
| III | 35 (17.8%) | 8 (16%) | 27 (18.4%) | ||
| IV | 119 (60.4%) | 36 (72%) | 83 (56.5%) | 0.176 | |
| V | 35 (17.8%) | 5 (10%) | 30 (20.4%) | ||
| Crescents | Cellular | 66 (33.5%) | 20 (40%) | 46 (31.3%) | 0.299 |
| Fibrocellular+fibrous | 68 (34.5%) | 25 (50%) | 43 (29.25%) | 0.01 | |
| Endocapillary proliferation | 133 (67.5%) | 39 (78%) | 94 (63.9%) | 0.081 | |
| Interstitial inflammation | 107 (54.3%) | 32 (64%) | 75 (51%) | 0.139 | |
| Fibrinoid necrosis | 27 (13.7%) | 9 (18%) | 18 (12.2%) | 0.343 | |
| Karrhyorexis | 23 (11.7%) | 7 (14%) | 16 (10.9%) | 0.611 | |
| Hyaline thrombi | 39 (19.8%) | 13 (26%) | 26 (17.7%) | 0.221 | |
| Wireloop lesions | 68 (34.5%) | 22 (44%) | 46 (31.3%) | 0.122 | |
| Glomerular leukocytosis | 23 (11.7%) | 4 (8%) | 19 (12.9%) | 0.676 | |
| Tubular atrophy | 119 (60.4%) | 41 (82%) | 78 (53.1%) | 0.001 | |
| Interstitial fibrosis | 96 (48.7%) | 28 (56%) | 68 (46.3%) | 0.255 | |
| Glomerular sclerosis | 69 (35%) | 16 (32%) | 53 (36.1%) | 0.669 | |
TMA, thrombotic microangiopathy.