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Urine osmolality in tolvaptan subjects who reported an aquaretic adverse event (AAE). All patient data points are plotted as circles. Box plot shows mean and interquartile range of fasting baseline urine osmolality. AC, aquaretic-continued; AD, aquaretic-discontinued; AE, adverse event; Discont., discontinued; max, maximum; min, minimum; NAD, non–aquaretic-discontinued.
