Skip to main content
. Author manuscript; available in PMC: 2019 Jan 1.
Published in final edited form as: Bioorg Med Chem. 2017 Nov 4;26(1):25–36. doi: 10.1016/j.bmc.2017.10.042

Figure 3. Hydrogen bond analysis of the water network near V4 and 9 from 5EK9.

Figure 3

(A) Co-crystal structure of 9 bound to BRD2-BD2 from chain A, with the missing W5 water highlighted in red; (B) Co-crystal structure of 9 bound to BRD2-BD2 from chain B. Hydrogen bonds involving water are depicted as broken lines.