Skip to main content
. Author manuscript; available in PMC: 2019 Jan 1.
Published in final edited form as: Bioorg Med Chem. 2017 Nov 11;26(1):65–76. doi: 10.1016/j.bmc.2017.11.018

Figure 2.

Figure 2

Overlay of the crystal structures of compound 1 in the active site of FtFabI (salmon) with two known FabI inhibitors - benzimidazole based FabI inhibitor in SaFabI (PDB ID 4NZ9) (cyan), and AFN1252 (PDB ID 4FS3) (beige). Compound 1 occupies the same region in the active site as known FabI inhibitors.