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Synergistic activities of N-carboxy pyrrolidine analogs in combination with colistin against MDR A. baumannii. MIC of compound and colistin in the clear well (well with lowest concentrations and no growth) is reported.
| Compound in combination with colistin | MIC of colistin in combination (μg/mL) | MIC of compound in combination (μg/mL) | ΣFIC | Effect |
|---|---|---|---|---|
| 1 | 0.78 | 25 | 0.25 | Synergy |
| 8 | 0.39 | 25 | 0.25 | Synergy |
| 12 | 0.78 | 12.5 | 0.31 | Synergy |
| 24 | 0.78 | 12.5 | 0.31 | Synergy |
