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. Author manuscript; available in PMC: 2019 Jan 1.
Published in final edited form as: Bioorg Med Chem. 2017 Nov 11;26(1):77–83. doi: 10.1016/j.bmc.2017.11.020

Figure 1.

Figure 1

a: X-ray crystal structure of TLR8 binding with ssRNA degradation products in two binding sites; b: Guanosine modifications used in the study; c: Close up view of UpG binding with TLR8 in the second binding site.