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. Author manuscript; available in PMC: 2019 Jan 1.
Published in final edited form as: Bioorg Med Chem. 2017 Nov 11;26(1):77–83. doi: 10.1016/j.bmc.2017.11.020

Figure 7.

Figure 7

Pathway of TLR8 activation and antagonism by ssRNAs containing different guanosine analogs. Arrows: activation; T-shaped arrow: antagonism; Dash arrow: weak interaction; c7G: 7-deazaguanosine; 7d8aI: 7-deaza-8-azainosine.