High affinity iron permease (Ftr1p) |
Acquisition of host iron |
[51,57] |
Ferrioxamine receptors (Fob1 and Fob2) |
Acquisition of iron from ferrioxamine |
[52] |
Fungal Spore coating protein (CotH) |
Invasion of the endothelium |
[47] |
Host Glucose regulated protein 78 (GRP78) |
Invasion of the endothelium |
[46,49] |
Host Platelet-derived growth factor receptor (PDGFR) |
Invasion of host cells |
[48] |
Spore size |
Faster germination |
[25] |
calcineurin pathway |
Regulation of hyphal growth |
[23,58] |
Uncharacterized toxins |
Host cell damage and possible induction of inflammatory response |
[32,44] |