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. Author manuscript; available in PMC: 2017 Dec 18.
Published in final edited form as: Ann Surg Oncol. 2015 Aug 20;23(2):655–662. doi: 10.1245/s10434-015-4778-7

FIG. 2.

FIG. 2

Complement depletion with CVF reduces immunosuppressive MDSCs and results in increased tumor infiltration of effector T cells via increased production of chemoattractive mediators. a FACS analysis shows increased percentage of CD11b+Gr1+ cells in splenocytes of PBS-treated mice vs. CVF-treated mice (p = 0.04563). b FACS analysis of tumor-infiltrating lymphocytes shows a higher percentage of CD8+ T cells in CVF-treated mice compared to control mice (p = 0.033) and c decreased percentage of CD4+ T cells infiltrating tumors in CVF-treated mice (p = 0.04). *p < 0.05, **p < 0.01, ***p ≤ 0.001