Table 1.
Characteristics of the study subjects
| Parameter | Control | CKD |
|---|---|---|
| Number (M/F) | 11 (3/8) | 16 (9/7) |
| Age (yr) | 45.6 ± 8.6 | 38.8 ± 14.8 |
| BMI (kg/m2) | 26.2 ± 2.9 | 22.7 ± 2.1d |
| GFR (ml/min) | 133 ± 32 | 12 ± 7d |
| CRP (mg/l) | 1.0 ± 0.9 | 7.5 ± 17.9 |
| Glucose (mmol/l)a | 5.2 ± 0.8 | 5.6 ± 1.0 |
| Na (mmol/l) | 141 ± 1 | 139 ± 4 |
| K (mmol/l) | 3.9 ± 0.2 | 4.8 ± 0.7d |
| Creatinine (μmol/l) | 63 ± 21 | 742 ± 284d |
| Urea (mmol/l)b | 4.6 ± 1.2 | 24.4 ± 9.4d |
| Bilirubin (μmol/l)b | 7 ± 2 | 8 ± 2 |
| ASAT (μkat/l) | 0.37 ± 0.07 | 0.33 ± 0.11 |
| Leukocytes (×109/l) | 6.3 ± 1.7 | 7.6 ± 2.4 |
| Hemoglobin (g/l) | 139 ± 10 | 113 ± 20d |
| Triglyceride (mmol/l)c | N/A | 1.7 ± 0.8 |
| Cholesterol (mmol/l)c | N/A | 4.8 ± 1.1 |
| HDL (mmol/l)c | N/A | 1.5 ± 0.6 |
ASAT, aspartate aminotransferase; BMI, body mass index; CKD, chronic kidney disease; CRP, C-reactive protein (measured with a high-sensitivity method); GFR, glomerular filtration rate (for males GFR = (1.23 × [140 − age] × weight)/serum creatinine; for females GFR = (1.04 × [140 − age] × weight)/serum creatinine]; HDL, high-density lipoprotein cholesterol; N/A, data not available.
Values are given as mean ± SD.
a
Data available from 14 CKD subjects.
b
Data available from 12 CKD subjects.
c
Data available from 15 CKD subjects.
d
P ≤ 0.01 for differences between groups (Student t test).