Table 4.
Relation of acute kidney injury stage at presentation with long-term outcome of estimated glomerular filtration rate in 62 Oklahoma patients who survived their initial episode of TTP and had follow-up serum creatinine measurements
| AKI stage | Patients | eGFR |
Follow-up duration | |||
|---|---|---|---|---|---|---|
| ≥90 | 60–89 | 45–59 | 30–44 | |||
| KDIGO 0 | 27 | 17 | 9 | 1 | – | 5.4 |
| KDIGO 1 | 21 | 14 | 5 | 1 | 1 | 8.1 |
| KDIGO 2 | 9 | 4 | 4 | 0 | 1 | 4.5 |
| KDIGO 3 | 5 | 4 | 1 | 0 | – | 8.1 |
| All patients | 62 | 39 | 19 | 2 | 2 | 6.4 |
AKI, acute kidney injury; eGFR, estimated glomerular filtration rate; KDIGO, Kidney Disease: Improving Global Outcomes.
Among the 78 patients in the Oklahoma Thrombotic Thrombocytopenic Purpura Registry, 68 survived their initial episode; 2 patients have been lost to follow-up, and 4 patients have not had follow-up serum creatinine concentration measurements. There was no association between KDIGO AKI stage and eGFR (P = 0.74). Dash indicates that no subjects had eGFR within this range.