. 2017 Dec 14;9:849–867. doi: 10.2147/CMAR.S151026

Table 2.

Correlation between SII and hematologic parameters

Parameters	NCT			P-value	NNCT			P-value
Parameters	Low SII <600	High SII ≥600	χ²	P-value	Low SII <600	High SII ≥600	χ²	P-value
Cases (n)	52	55			117	68
White blood cell (W)			15.680	<0.001			6.578	0.010
<6.17	33	14			71	28
≥6.17	19	41			46	40
Hb			6.765	0.009			16.530	<0.001
<126	24	39			38	43
≥126	28	16			79	25
Neutrophils (N)			28.230	<0.001			28.660	<0.001
<3.74	39	13			77	17
≥3.74	13	42			40	51
Monocyte (M)			2.058	0.151			1.146	0.284
<0.42	21	15			68	34
≥0.42	31	40			49	34
Platelet (P)			19.190	<0.001			18.100	<0.001
<262	32	11			79	24
≥262	20	44			38	44
Lymphocyte (L)			0.448	0.503			17.090	<0.001
<1.74	25	30			44	47
≥1.74	27	25			73	21
NLR			29.340	<0.001^*			44.610	<0.001
<1.65	24	1			57	1
≥1.65	28	54			60	67
MLR			67.501	<0.001			6.600	0.010
<0.17	46	5			35	9
≥0.17	6	50			82	59
PLR			33.400	<0.001^*			47.790	<0.001
<133	28	2			77	9
≥133	24	53			40	59

Notes:

Fisher’s exact test. SII is a novel systemic immune–inflammation index (SII=N×P/L), which is based on neutrophil (N), platelet (P) and lymphocyte (L) counts.

Abbreviations: Hb, hemoglobin; MLR, monocyte to lymphocyte ratio; NCT, neoadjuvant chemotherapy; NLR, neutrophil to lymphocyte ratio; NNCT, non-neoadjuvant chemotherapy; PLR, platelet to lymphocyte ratio.