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. 2017 Dec 4;2017:7142370. doi: 10.1155/2017/7142370

Table 2.

Biological experiments from isolated constituents from Dalbergia odorifera species.

Number Compounds Biological experiments References
3 4′,5,7-Trihydroxy-3-methoxyflavone Antioxidant [19]
4 Formononetin Alpha-glucoside inhibition, antibacterial, antioxidant, anti-inflammatory, cytotoxicity [3, 2326]
5 2′-O-Methylformononetin Anti-inflammatory [24]
6 Daidzein Anti-inflammatory [24]
8 3′-Methoxydaidzein Antioxidant [19]
10 7,3′-Dihydroxy-5′-methoxyisoflavone Alpha-glucoside inhibition, anti-inflammatory [28, 29]
11 Tectorigenin Alpha-glucoside inhibition, cytotoxicity [3, 23]
12 Koparin Anti-inflammatory [18]
13 Xenognosin B Anti-inflammatory [18]
16 Biochanin A Antioxidant [33]
17 Biochanin B Antioxidant [33]
18 Olibergin A Anti-inflammatory [24]
19 Orobol Anti-inflammatory [24]
20 Bowdichione Anti-inflammatory [18]
21 (2S)-Liquiritigenin Alpha-glucoside inhibition, antibacterial, cytotoxicity [3, 23, 29, 34]
22 Eriodictyol Antioxidant [33]
23 Naringenin Antioxidant [33]
24 (2S)-Pinocembrin Alpha-glucoside inhibition, antioxidant, anti-inflammatory [24, 29, 33]
26 (2S)-Pinostrobin Anti-inflammatory [24]
27 (2S)-3′,5,5′,7-Tetrahydroxyflavanone Anti-inflammatory [24]
28 (2S)-7-Methoxy-4′,6-dihydroxyflavanone Anti-inflammatory [24]
29 Carthamidin Antibacterial [34]
31 6,4′-Dihydroxy-7-methoxyflavanone Anti-inflammatory [28, 43]
32 (2S)-6,7,4′-Trihydroxyflavan Anti-inflammatory [28]
33 (2S)-6,4′-Dihydroxy-7-methoxyflavan Alpha-glucoside inhibition, anti-inflammatory [28, 29]
34 6,7-Dimethoxy-2-(4-methoxybenzoquinonyl)-flavan Cytotoxicity [35]
35 (3R)-Sativanone Alpha-glucoside inhibition, antibacterial, antioxidant, anti-inflammatory [24, 29, 33, 34]
36 (3R)-Violanone Anti-inflammatory [24]
37 (3R)-3′-O-Methylviolanone Anti-inflammatory [18, 24]
38 (3R)-Vestitone Antibacterial [34]
39 (3S)-2′,4′,5′-Trimethoxy-7-hydroxyisoflavanone Anti-inflammatory [24]
40 (3R)-2′,3′,7-Trihydroxy-4′-methoxyisoflavanone Antioxidant, antibacterial [19, 20, 34]
41 (3R)-4′-Methoxy-2′,3,7-trihydroxyisoflavanone Anti-inflammatory, antibacterial [24, 34]
42 (3S)-2′,4′-Dimethoxy-3,7-dihydroxyisoflavanone Anti-inflammatory [24]
43 (3R)-7,3′-Dihydroxy-6,2′,4′-trimethoxyisoflavanone Antibacterial, cytotoxicity [7]
44 (3R)-Vestitol Antioxidant, antibacterial, cytotoxicity, PG synthetase inhibition [19, 21, 22, 34]
45 (3R)-5′-Methoxyvestitol Alpha-glucoside inhibition, antioxidant, cytotoxicity [3, 23, 25]
48 Isoduratin PG synthetase inhibition [21, 22]
49 Mucronulatol Alpha-glucoside inhibition, cytotoxicity, PG synthetase inhibition [3, 2123]
50 (3R)-Calussequinone Alpha-glucoside inhibition, antibacterial, cytotoxicity [3, 23, 26]
51 7-Hydroxy-5′-methoxyspiro[benzo[d][1,3]dioxole-2′,3-chroman]-4-one Cytotoxicity [35]
52 Odoriflavene Antioxidant, cytotoxicity, PG synthetase inhibition [21, 22, 25]
55 Melanettin Anti-inflammatory [24]
56 3′-Hydroxymelanettin Antioxidant, anti-inflammatory [24, 33]
57 R(−)-Latifolin Alpha-glucoside inhibition, anti-inflammatory [24, 28, 29, 37]
58 R(−)-5-O-Methylatifolin Anti-inflammatory [28]
59 R(−)-Dalbergiphenol Anti-inflammatory [28]
60 9-Hydroxy-6,7-dimethoxydalbergiquinol Anti-inflammatory [5, 28]
61 4,5-Dimethoxy-2-hydroxydalbergiquinol Anti-inflammatory [24]
62 2,4,5-Trimethoxy-3′-hydroxydalbergiquinol Anti-inflammatory [24]
65 Isoliquiritigenin Alpha-glucoside inhibition, antibacterial, anti-inflammatory [18, 24, 28, 29, 34, 44]
66 2′-O-Methyl-isoliquiritigenin Antioxidant, cytotoxicity [25]
67 4,2′,5′-Trihydroxy-4′-methoxychalcone Anti-inflammatory [28, 45]
68 Butein Anti-inflammatory, vasorelaxant activity [24, 46, 47]
69 α,2′,3,4,4′-Pentahydroxydihydrochalcone Anti-inflammatory [24]
70 α,2′,4,4′-Tetrahydroxydihydrochalcone Anti-inflammatory [24]
71 Medicarpin Alpha-glucoside inhibition, antibacterial, antioxidant, anti-inflammatory, cytotoxicity [3, 19, 23, 26], [39]∗∗
72 (6aR,11aR)-6a,9-Dimethoxy-3-hydroxypterocarpan Cytotoxicity [7]
73 (6aR,11aR)-6a,3,9-Trimethoxypterocarpan Antibacterial, cytotoxicity [7]
74 (6aR,11aR)-Variabiin Antibacterial, cytotoxicity [7]
75 Vesticarpan Cytotoxicity [7]
76 3-Methoxy-9-hydroxypterocarpan Antibacterial, cytotoxicity [7]
77 Meliotocarpan A Antibacterial, cytotoxicity [7]
79 Meliotocarpan D Antibacterial, cytotoxicity [7]
92 2-(2-(2,4-Dimethoxyphenyl)-2-oxoethoxy)-4-hydrobenzoic acid Antibacterial, cytotoxicity [7]
93 2-(2,4-Dihydroxyphenyl)-1-(4-hydroxy-2-methoxyphenyl)ethanone Cytotoxicity [7]
94 Obtustyrene PG synthetase inhibition [21, 22]
95 Hydroxyobtustyrene Cytotoxicity, PG synthetase inhibition [2123]
96 Isomucronustyrene PG synthetase inhibition [21, 22]
97 Cearoin Anti-inflammatory [18, 28]
98 2,2′,5-Trihydroxy-4-methoxybenzophenone Anti-inflammatory [28]
99 2,4-Dihydroxy-5-methoxybenzophenone Antioxidant [19]
100 Methyl-2-hydroxy-3,4-dimethoxybenzoate PG synthetase inhibition [21, 22]
101 2-Hydroxy-3,4-dimethoxybenzaldehyde Cytotoxicity [23]
102 6α-Hydroxycyclonerolidol Antibacterial [41]
103 Rel-(3R,6R,7S)-3,7,11-Trimethyl-3,7-epoxy-1,10-dodecadien-6-ol Antibacterial [41]
104 Rel-(3S,6R,7S,10S)-2,6,10-Trimethyl-3,6,7,10-diepoxy-2-dodecen-11-ol Antibacterial [41]
105 Rel-(3S,6R,7S,10R)-2,6,10-Trimethyl-3,6,7,10-diepoxy-11-dodecen-2-ol Antibacterial [41]
106 Rel-(2R,2′R,5′S)-2,5′-Dimethyl-5′-vinylhexahydro-2,2′-bifuran-5(2H)-one Antibacterial [41]
107 Crocinervolide Antibacterial [41]
108 Neroplofurol Antibacterial [41]
109 Rel-(3S,6R,7S,9E)-3,7,11-Trimethyl-3,6-epoxy-1,9,11-dodecatrien-7-ol Antibacterial [41]
110 Rel-(3S,6R,7S)-3,7,11-Trimethyl-3,6-epoxy-1-dodecen-7,11-diol Antibacterial [41]
111 Rel-(3S,6R,7S)-3,7,11-Trimethyl-3,6-epoxy-1,10-dodecadien-7-ol Antibacterial [41]
112 Rel-(3S,6S,7R)-3,7,11-Trimethyl-3,6-epoxy-1,10-dodecadien-7-ol Antibacterial [41]
113 (3S,6R,7R)-3,7,11-Trimethyl-3,6-epoxy-1,10-dodecadien-7-ol Antithrombotics, antiplatelet [42]
114 (3S,6S,7R)-3,7,11-Trimethyl-3,6-epoxy-1,10-dodecadien-7-ol Antithrombotics, antiplatelet [42]
115 (E)-7-Hydroxy-6,10-dimethylundeca-5,9-dien-2-one Antibacterial [41]
116 3,7,11-Trimethyldodeca-1,10-diene-3,6,7-triol Antibacterial [41]
117 (3S,5E)-3,11-Dimethyl-7-methylenedodaca-1,5,10-trien-3-ol Antibacterial [41]
118 Rel-(S,E)-2-[(S)-2,2-Dimethyl-1,3-dioxolan-4-yl]-6,10-dimethylundeca-5,9-dien-2-ol Antibacterial [41]
119 (2R,3R)-Obtusafuran Anti-inflammatory [4, 28]
120 6-Methoxy-5,2′,4′-trihydroxy-3-benzoylbenzofuran Antibacterial, cytotoxicity [7]
121 Phenylbenzofuran I Cytotoxicity [35]
122 Sulfuretin Antibacterial [34]
123 Isoparvifuran Anti-inflammatory [4, 28]
124 2′,6-Dihydroxy-4′-methoxy-2-arylbenzofuran
(6-hydroxy-2-(2-hydroxy-4-methoxyphenyl)benzofuran)
Anti-inflammatory [39]
125 (S)-4-Methoxydalbergione Anti-inflammatory, antiosteosarcoma [18, 48]
126 R(+)-4-Methoxydalbergione Anti-inflammatory, antiosteosarcoma [28, 38]
127 4′-Hydroxy-4-methoxydalbergione Anti-inflammatory [28]
128 2-Methoxy-3-hydroxyxanthone Anti-inflammatory [24]
129 Hexanoic acid, 2-propenyl ester Antioxidant [19]
130 Hexadecanoic acid, ethyl ester Antioxidant [19]
131 3,8-Nonadien-2-one Antioxidant [19]