Table 3.
KEGG pathways related to sex hormones and lipolysis, significantly enriched (adjusted p-value of ≤0.05) by predicted targets of Coicis Semen.
| Rank | KEGG pathway | Adjusted- p value |
Genes (targets) |
|---|---|---|---|
| 5/63 | hsa04923: Regulation of lipolysis in adipocytes |
3.86E − 06 | Beta-1 adrenergic receptor; beta-2 adrenergic receptor; prostaglandin G/H synthase 2; mRNA of PKA catalytic subunit C-alpha; prostaglandin G/H synthase 1 |
|
| |||
| 39/63 | hsa04914: Progesterone-mediated oocyte maturation |
4.51E − 03 | Cell division protein kinase 2; progesterone receptor; mRNA of PKA catalytic subunit C-alpha |
|
| |||
| 40/63 | hsa04915: Estrogen signaling pathway |
4.52E − 03 | Nitric oxide synthase; mRNA of PKA catalytic subunit C-alpha; estrogen receptor |
|
| |||
| 48/63 | hsa04921: Oxytocin signaling pathway |
0.014 | Nitric oxide synthase; mRNA of PKA catalytic subunit C-alpha; prostaglandin G/H synthase 2 |