Table 3.

Characteristics of the Original Aurora AF Warfarin and Aurora Clinical Avatar Populations

Characteristic	Aurora AF Warfarin Population (mean±SD)	Aurora Clinical Avatar Population (mean±SD)
Age, year,	67.3±14.43	67.2±14.47
Weight, lb,	199.24±54.71	199.24±54.6
Height, in,	66.78±4.31	66.53±4.32
Gender, %
Female	53.14	53.10
Male	46.86	46.90
Race, %
White	95.18	95.22
African-American	4.25	4.19
Asian	0.39	0.40
Am. Indian/Alaskan	0.18	0.18
Pacific Islander	0.0001	0.0001
Tobacco, %
No	90.33	90.67
Yes	9.66	9.33
Amiodarone, %
No	88.45	88.49
Yes	11.54	11.51
Fluvastatin, %
No	99.97	99.98
Yes	0.03	0.02
CYP2C9, %
*1/*1	65.77*	67.39
*1/*2	14.6*	14.86
*1/*3	9.11*	9.25
*2/*2	6.41*	6.51
*2/*3	1.93*	1.97
*3/*3	0*	0
VKORC1, %
G/G	38.54*	38.37
G/A	44.02*	44.18
A/A	17.33*	17.45

^*Aurora patient population’s genotypic characteristics were derived from published genotype distributions.³⁵