Table 2.
Baseline characteristics and clinical outcomes of patients in the two study cohorts after matching (matched data)
| Variable | Amylase (U/L)
|
P-values | |
|---|---|---|---|
| ≥300 (n=108) | <300 (n=108) | ||
| Age (years) | 41.2±11.7 | 41.5±11.9 | 0.854 |
| Male gender | 77 (71.3) | 77 (71.3) | 1.00 |
| Time interval before admission (days) | 2.0±0.8 | 2.0±0.8 | 0.930 |
| BMI (kg/m2) | 24.3±3.5 | 24.4±4.2 | 0.959 |
| Hypertension | 25 (23.4) | 21 (19.4) | 0.506 |
| Diabetes mellitus | 16 (14.8) | 23 (21.3) | 0.216 |
| Fatty liver | 45 (41.7) | 58 (53.7) | 0.077 |
| Alcohol consumption | 20 (18.5) | 26 (24.1) | 0.319 |
| Smoking | 38 (35.2) | 36 (33.3) | 0.774 |
| Etiology | 0.020 | ||
| Biliary | 37 (34.3) | 17 (15.7) | |
| Hypertriglyceridemia | 5 (4.6) | 12 (11.1) | |
| Alcohol | 20 (18.5) | 26 (24.1) | |
| Idiopathic | 42 (38.9) | 49 (45.5) | |
| Other | 4 (3.7) | 4 (3.7) | |
| Laboratory findings | |||
| Amylase day 1 (U/L) | 747 (483–1,272) | 160 (105–215) | <0.001 |
| Amylase day 2 (U/L) | 341 (184–587) | 80 (57–146) | <0.001 |
| Hematocrit (mg/dL) | 0.43±0.06 | 0.43±0.06 | 0.649 |
| Glucose (mg/dL) | 165±72 | 167±75 | 0.842 |
| BUN (mg/dL) | 12.3 (9.2–16.0) | 11.3 (9.2–14.7) | 0.247 |
| Creatinine (mg/dL) | 0.75 (0.62–0.84) | 0.74 (0.59–0.87) | 0.914 |
| Total cholesterol (mg/dL) | 183 (142–224) | 237 (190–322) | <0.001 |
| HDL-C (mg/dL) | 38 (27–45) | 35 (24–48) | 0.728 |
| LDL-C (mg/dL) | 89 (72–119) | 105 (78–131) | 0.031 |
| Triglyceride levels (mg/dL) | 129 (75–304) | 309 (150–643) | <0.001 |
| Outcomes | |||
| Severity of acute pancreatitis | 0.846 | ||
| Mild | 82 (75.9) | 85 (78.7) | |
| Moderately severe | 17 (15.7) | 16 (14.8) | |
| Severe | 9 (8.3) | 7 (6.5) | |
| Median hospital stay (days) | 10.5 (7–15) | 9.5 (7–12) | 0.152 |
| Death | 3 (2.8) | 1 (0.9) | 0.313 |
Note: Data are presented as mean ± standard deviation, or numbers (%), or median (25th–75th percentile), as appropriate.
Abbreviations: BMI, body mass index; BUN, blood urea nitrogen; HDL-C, high-density lipoprotein cholesterol; LDL-C, low-density lipoprotein cholesterol.