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. 2017 Jun 14;7(6):e015447. doi: 10.1136/bmjopen-2016-015447

Table 1.

Principal results comparing use of an antimicrobial resistance point-of-care test (AMR POCT) for ciprofloxacin (scenario 3a) or penicillin resistance (scenario 3b) against current testing practice (standard laboratory testing, no POCT) for the management of gonorrhoea (scenario 1), assuming the current attendance at genitourinary medicine clinic annually

Heterosexual male MSM Female Overall
Considering use of POCT test for ciprofloxacin resistance
Annual ceftriaxone treatments
 Current (scenario 1) 7690 17 691 8050 33 431
 AMR POCT (scenario 3a) 2188 7933 1257 11 378
 Reduction under scenario 3a 5502 9759 6793 22 054
 Percentage reduction in ceftriaxone 72 55 84 66
Proportion treated same day (%)
 Current (scenario 1) 68 63 21 54
 AMR POCT (scenario 3a) 100 100 100 100
 Increase under scenario 3a 32 37 79 46
Mean time to treatment (days)
 Current (scenario 1) 1.5 1.8 3.9 2.2
 AMR POCT (scenario 3a) 0.0 0.0 0.0 0.0
 Reduction under scenario 3a 1.5 1.8 3.9 2.2
Persons lost to follow-up (untreated)
 Current (scenario 1) 125 338 329 792
 AMR POCT (scenario 3a) 0 0 0 0
Considering use of POCT test for penicillin resistance
Annual ceftriaxone treatments*
 Current (scenario 1) 7690 17 691 8050 33 431
 AMR POCT (scenario 3b) 1407 4688 838 6932
 Reduction under scenario 3b 6283 13 004 7212 26 499
 Percentage reduction in ceftriaxone 82 74 90 79

*All other outcomes same as for use of POCT for ciprofloxacin resistance. Results for strategy 2 not shown: equivalent to strategy 3 except for choice of antibiotic treatment. Results for 3b also equivalent to 3a for outcomes except reduction in ceftriaxone treatments.

MSM, men who have sex with men.