Table 2.
Outcome measure | Median (IQR) | rs (95% CI)b |
---|---|---|
Physical health outcomes | ||
6MWT (m) | 435 (354–512) | −0.70 (−0.75 to −0.65) |
CPET (W) | 64 (47–87) | −0.44 (−0.52 to −0.37) |
IQPT (J) | 91.4 (66.0–118.6) | −0.33 (−0.42 to −0.25) |
Symptom-related outcomes | ||
mMRC (points) | 2 (2–3) | 0.49 (0.42 to 0.56) |
CAT (points) | 22 (17–26) | 0.27 (0.19 to 0.36) |
SGRQ-C | ||
Symptoms (points) | 63.1 (48.5–76.1) | 0.18 (0.09 to 0.27) |
Activity (points) | 83.6 (67.8–92.2) | 0.39 (0.31 to 0.46) |
Impact (points) | 51.2 (34.2–64.1) | 0.40 (0.32 to 0.47) |
Total (points) | 63.6 (49.9–74.2) | 0.41 (0.33 to 0.48) |
Multidimensional indices | ||
ADO index (points) | 4 (3–6) | 0.52 (0.45 to 0.58) |
Updated BODE index (points) | 3 (2–6) | 0.55 (0.49 to 0.61) |
Mental health outcomes | ||
HADS anxiety (points) | 7 (4–11) | 0.21 (0.12 to 0.30) |
HADS depression (points) | 7 (4–11) | 0.26 (0.17 to 0.34) |
6MWT: 6-minute walk test; BODE: body mass index, airflow obstruction, dyspnoea and exercise capacity index; CAT: COPD assessment test; CPET: cardiopulmonary exercise test; HADS: hospital anxiety and depression scale; IQPT: isokinetic quadriceps peak torque; mMRC: modified medical research council; SGRQ-C: COPD version for the St George’s respiratory questionnaire; COPD: chronic obstructive pulmonary disease; ADO: age, dyspnoea and obstruction; IQR: interquartile range.
aIncomplete data for certain variables: 6MWT, n = 497; CPET, n = 479; IQPT, n = 452; mMRC, n = 495; HADS, n = 485; CAT and SGRQ, n = 488; ADO index, n = 495 and updated BODE index, n = 492.
bAll p-values were < 0.0001.