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. 2017 Jun 24;7(6):e015557. doi: 10.1136/bmjopen-2016-015557

Table 4.

Trials comparing glibenclamide to metformin

First author Year Location No Diagnostic test and thresholds used to diagnose GDM (mmol/L) Screening strategya Outcome
George76 2015 India 159 100 g OGTT two or more; fasting >5.3 or 1 hour >10.0 or 2 hours >8.6 Not reported BW, GA at birth, macrosomia, hypoglycaemia
Moore75 2010 USA 149 100 g OGTT two or more; fasting >5.3 or 2 hours >6.7 50 g OGCT>7.2 BW, C-section, GA at birth, macrosomia, hypoglycaemia, NICU admission, pre-eclampsia, shoulder dystocia
Silva77 2012 Brazil 200 75 g OGTT fasting >5.3 or 1 hour >10.0 or 2 hours >8.0 No screening Apgar 5 min, BW, C-section, GA at birth, LGA, macrosomia, hypoglycaemia, NICU admission

BW, birth weight; C-section, caesarean section; GA, gestational age; GDM, gestational diabetes mellitus; LGA, large for gestational age; NICU, neonatal intensive care unit.