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. 2017 Nov 22;13:1744806917746564. doi: 10.1177/1744806917746564

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© The Author(s) 2017

This article is distributed under the terms of the Creative Commons Attribution-NonCommercial 4.0 License (http://www.creativecommons.org/licenses/by-nc/4.0/) which permits non-commercial use, reproduction and distribution of the work without further permission provided the original work is attributed as specified on the SAGE and Open Access pages (https://us.sagepub.com/en-us/nam/open-access-at-sage).

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Figure 5. — Repeated administration of T10, MK-801, or their combination reversed SNL-induced mechanical allodynia. (a–b) The continual analgesia duration of i.t. administration of T10, MK-801 or their combination after terminating drug treatment. (c–d) The AUCs for the different groups were calculated to perform statistical analyses. ⋆P < 0.001, SNL saline group versus sham saline group; *P < 0.05 and **P < 0.01, SNL-T10 group versus SNL saline group; ^#P < 0.05, SNL-MK-801 group versus SNL saline group; ★★★P < 0.001, SNL-T/M (1/3) group versus SNL saline group; ♦P < 0.05 and ♦♦♦P < 0.001, SNL-T/M (1/1) group versus SNL saline group; ^&P < 0.05 and ^&&&P < 0.001, SNL-T/M (3/1) group versus SNL saline group; ▾▾P < 0.01, SNL-T/M (1/3) group versus SNL-T/M (3/1) group and SNL-T/M (1/1) group, respectively. AUC: area under curve; SNL: spinal nerve ligation.