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. 2017 Jul 2;7(6):e014581. doi: 10.1136/bmjopen-2016-014581

Figure 5.

Figure 5

Hierarchical meta-analysis of trough levels of antibodies to infliximab for predicting loss of response or failure to regain response. Top left, all 20 studies; top right, ELISA studies only (n=9); lower left, all studies minus two influential studies (n=18)26 66; lower right, responder studies only (n=13). The square symbol represents the summary point estimate on the hierarchical summary receiver operating characteristic (HSROC) curve.