Table 2.
Baseline hepcidin, prohepcidin [10] and α-1-antitrypsin concentrations in relation to the control group values, depending on response (R) or non-response (NR) to treatment. Values given as mean ± SE
| Factor | Control group | Genotype 1b | Genotype 3a | All patients | |||
|---|---|---|---|---|---|---|---|
| NR | R | NR | R | NR | R | ||
| Hepcidin (ng/ml) | 55.7 ± 9.6 | 219 ± 37* | 261 ± 58* | 129 ± 42 | 208 ± 42* | 201 ± 31* | 234 ± 35* |
| Prohepcidin (ng/ml) | 84.1 ± 7.8 | 88.3 ± 11.5 | 88.9 ± 14.7 | 94.1 ± 8.0 | 99.5 ± 5.2 | 89.2 ± 9.7 | 85.4 ± 6.4 |
| α-1-antitrypsin (mg/dl) | 51.7 ± 6.0 | 60.6 ± 7.3 | 62.0 ± 7.3 | 92.5 ± 8.2*# | 56.2 ± 8.3# | 67.0 ± 6.8 | 59.0 ± 5.5 |
*
Statistically significant (p < 0.05) differences compared to normal.
#
Statistically significant differences between NR and R groups.