Table 1.
Variable | D-Cycloserine Plus CBT (n = 70) |
Placebo Plus CBT (n = 72) |
P Value |
---|---|---|---|
Age, mean (SE), y | 13.05 (2.93) | 12.54 (3.04) | .31a |
Female sex, No. (%) | 42 (60.0) | 34 (47.2) | .13b |
White race/ethnicity, No. (%) | 61 (87.1) | 65 (90.3) | .55b |
CY-BOCS at randomization, mean (SE) | 24.74 (5.91) | 23.96 (4.91) | .39a |
Overall comorbidities, No. (%) | |||
OCD only | 11 (15.9) | 13 (18.6) | |
OCD and 1 additional | 26 (37.7) | 15 (21.4) | .14c |
OCD and 2 additional | 13 (18.8) | 22 (31.4) | |
OCD and 3 or more | 19 (27.5) | 20 (28.6) | |
Specific comorbid conditions, No. (%) | |||
Generalized anxiety disorder | 18 (26.1) | 23 (31.4) | .49b |
Socialphobia | 6 (23.2) | 9 (12.7) | .10b |
Attention-deficit/hyperactivity disorder | 20 (29.4) | 17 (23.6) | .44b |
Depressive disorder | 11 (15.9) | 10 (13.9) | .73b |
Separation anxiety disorder | 9 (13.2) | 4 (5.6) | .12b |
Psychotropic medication, % | |||
Serotonin reuptake inhibitor | 17 (24.3) | 25 (34.7) | .17b |
Atypicalantipsychotic | 0 | 3 (4.2) | .08b |
Stimulant | 4(5.7) | 3 (4.2) | .67b |
Abbreviations: CBT, cognitive behavior therapy; CY-BOCS, Children’s Yale-Brown Obsessive Compulsive Scale; OCD, obsessive-compulsive disorder.
Analysis of variance F1,140.
Test.
Test.