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. Author manuscript; available in PMC: 2017 Dec 18.
Published in final edited form as: JAMA Psychiatry. 2016 Aug 1;73(8):779–788. doi: 10.1001/jamapsychiatry.2016.1128

Table 2.

Parameter Estimates for Random-Effects Models on Outcomes

Variable β (SE)
CY-BOCS CGI-Severity CY-BOCS Compulsions CY-BOCS Obsessions CDRS MASC COIS-P
Fixed effects
Intercept 23.83 (0.93)a   3.50 (0.13)a 12.59 (0.49)a 11.88 (0.51)a 44.29 (1.69)a 40.97 (3.64)a 16.15 (1.61)a
Time −2.03 (0.23)a −0.23 (0.03)a −1.08 (0.13)a −1.00 (0.13)a −1.15 (0.36)b −1.63 (0.56)b −1.43 (0.24)a
Site −1.80 (1.31) −0.14 (0.19) −1.08 (0.69) −1.37 (0.71)   3.72 (2.47) −2.88 (5.13) −2.54 (2.28)
Group   1.32 (1.31)   0.25 (0.19)   0.59 (0.69)   0.27 (0.72) −2.09 (2.39)   7.27 (5.12) −2.02 (2.27)
Group × site   0.13 (1.86) −0.04 (0.27)   0.03 (0.97)   0.55 (1.00)   5.34 (3.59)   1.13 (7.33)   6.97 (3.24)c
Site × time   0.29 (0.33) −0.01 (0.04)   0.15 (0.17)   0.20 (0.18) −0.33 (0.53)   0.35 (0.80)   0.56 (0.34)
Group × time −0.28 (0.33) −0.05 (0.04) −0.14 (0.18) −0.14 (0.18)   1.02 (0.50)c   0.23 (0.80)   0.21 (0.34)
Group × site × time   0.19 (0.47)   0.03 (0.06)   0.15 (0.24)   0.03 (0.26)   0.13 (0.78) −0.35 (1.15) −0.65 (0.49)
Random effects
Residual 10.70 (0.74)a   0.25 (0.02)a   3.49 (0.25)a   3.69 (0.26)a 45.38 (5.95)a 54.89 (7.28)a 21.42 (2.77)a
Intercept 25.16 (3.68)a   0.50 (0.08)a   6.18 (0.98)a   6.62 (1.04)a 67.27 (13.78)a 416.77 (55.91)a 74.65 (11.40)a
Slope   1.23 (0.24)b   0.02 (0.00)a   0.29 (0.07)a   0.33 (0.07)a   0.81 (0.75)   6.24 (1.47)a   0.27 (0.33)
Correlation −0.25 (0.11)a −0.09 (0.13) −0.21 (0.12) −0.23 (0.12) −0.16 (0.27) −0.41 (0.10)a −0.11 (0.27)

Abbreviations: CDRS, Children’s Depression Rating Scale; CGI-Severity, Clinical Global Impressions-Severity; COIS-P, Children’s Obsessive-Compulsive Impact Scale-Parent Version; CY-BOCS, Children’s Yale-Brown Obsessive Compulsive Scale; MASC, Multi dimensional Anxiety Scale for Children.

a

P <.001.

b

P < .01.

c

P < .05.