Table 4.
Percentage of Treatment Responders and Remitters as a Function of Group Statusa
Variable | Responders, No. (%) | Group Comparison | ||
Placebo Plus CBT | D-Cycloserine Plus CBT | Statistic | P Value | |
CY-BOCS <14 | ||||
Visit 7 | 9 (12.5) | 12 (17.1) | 0.61 | .44 |
Visit 8 | 15 (20.8) | 12 (17.1) | 0.31 | .58 |
Visit 9 | 27 (37.5) | 23 (32.9) | 0.34 | .56 |
Posttreatment | 44 (61.1) | 42 (60.0) | 0.02 | .89 |
CY-BOCS <12 | ||||
Visit 7 | 4 (5.6) | 11 (15.7) | 3.88 | .05 |
Visit 8 | 11 (15.3) | 1 (10.0) | 0.89 | .35 |
Visit 9 | 15 (20.8) | 13 (18.6) | 0.11 | .74 |
Posttreatment | 33 (45.8) | 35 (50.0) | 0.25 | .62 |
CGI-Improvement | ||||
Visit 8 | 38 (52.8) | 24 (34.3) | 4.93 | .03 |
Posttreatment | 52 (72.2) | 58 (82.9) | 2.29 | .13 |
Abbreviations: CBT, cognitive behavior therapy; CGI-Improvement, Clinical Global Impressions- Improvement; CY-BOCS, Children’s Yale-Brown Obsessive Compulsive Scale.
Ratings of very much and much improved on the CGI-Improvement were used to classify treatment response status.