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. Author manuscript; available in PMC: 2018 Nov 1.
Published in final edited form as: Ann N Y Acad Sci. 2017 Nov;1408(1):61–78. doi: 10.1111/nyas.13559

Figure 6.

Figure 6

Cobinamide is efficacious in treating neurotoxicity when administered up to 30 min after H2S exposure. (A and B) H2S-induced lesion severity with Cob treatment was observed up to 30 min after H2S exposure. Vacuolization, neurodegeneration, and gliosis are present in the inferior colliculus and, to a lesser extent, in the thalamus of animals exposed to H2S (arrows). * P < 0.05, ** P < 0.01 versus H2S/saline group. Representative photomicrographs of the inferior colliculus and thalamus (hematoxylin and eosin staining).