Increased production of proinflammatory cytokines in striatum of mice after introduction to LPS. (A) ELISA measurement of TNF-α, IL-Iβ, and IL-6 and INF-γ protein in striatum homogenate on experimental days 5, 19, and 36. LPS produced pronounced elevation of proinflammatory cytokines on day 5. (B) ELISA measurement of IL-10 protein in striatum during experimental course with PBS or LPS showed elevation on experimental days 36. Data represent mean ± SEM of 4-5 mice/group, *p < 0.05 for treatment effects.