Table 3.

Risk of AS with a history of multiple siblings with AS.

	N	HR	95% CI*
One sibling**	616	3.26	2.13–7.58
Two or more siblings**	34	32.84	20.47–65.17

^*Adjusted for dependence between the sibling pairs.

^†: Full model, adjusted for gender, birth year, family size, and comorbidities.

AS: Aortic stenosis. N: Number of AS cases.