Table 2.
| Non-exercised | 6h | 10h | ||||
|---|---|---|---|---|---|---|
| Control | IL-6 MKO | Control | IL-6 MKO | Control | IL-6 MKO | |
| Plasma IL-6 (pg/ml) | 5.5±1.3 | 3.5±0.1 | 20.0±8.8 | 12.5±3.2 | 5.1±1.0 | 2.2±0.4 |
| SkM IL-6 mRNA/TBP mRNA (AU) | 1.1±0.2 | 1.2±0.2 | 1.5±0.2 | 0.6±0.2# | 1.8±0.2 | 1.2±0.2# |
| SkM SOCS3 mRNA/TBP mRNA (AU) | 1.1±0.1 | 1.2±0.1 | 1.1±0.2 | 1.2±0.1 | 1.4±0.2 | 1.7±0.3 |
Plasma levels of IL-6 and Skeletal muscle IL-6 and SOCS3 mRNA content in non-exercised mice as well as 6h and 10h after 2h of treadmill running in Control and IL-6 MKO mice. SkM mRNA is given in arbitrary units (AU). Values are mean ± SE (n = 9–10)
*: significantly different from non-exercised mice within given genotype (p<0.05),
#: significantly different from Control within given time point (p<0.05).