Table 4.
| Non-exercised | 6h | 10h | ||||
|---|---|---|---|---|---|---|
| SkM | Control | IL-6 MKO | Control | IL-6 MKO | Control | IL-6 MKO |
| AMPKThr172 | 0.86(±0.06) | 0.82(±0.05) | 0.70(±0.05)* | 0.63(±0.06) | 0.71(±0.03)* | 0.81(±0.06) |
| AMPKα2 | 0.95(±0.03) | 0.91(±0.04) | 0.88(±0.03) | 0.90(±0.04) | 0.86(±0.04) | 0.90(±0.03) |
| ACC2 | 0.67(±0.06) | 0.73(±0.07) | 0.63(±0.09) | 0.60(±0.06) | 0.67(±0.05) | 0.66(±0.03) |
| PDHSer232 | 1.30(±0.33) | 1.60(±0.53) | 1.93(±0.35) | 1.99(±0.53) | 1.37(±0.27) | 0.78(±0.26) |
| PDHSer293 | 1.22(±0.08) | 1.30(±0.08) | 1.18(±0.07) | 1.19(±0.06) | 1.37(±0.10) | 1.03(±0.1) |
| PDH E1α | 1.04(±0.05) | 1.03(±0.08) | 0.96(±0.04) | 0.99±(0.06) | 1.11(±0.04) | 0.99±(0.07) |
| LDH | 1.06(±0.08) | 1.09(±0.07) | 1.16(±0.07) | 1.10(±0.09) | 1.11(±0.05) | 1.06(±0.03) |
| GLUT4 | 1.07(±0.03) | 1.05(±0.13) | 1.05(±0.06) | 1.02(±0.05) | 1.05(±0.05) | 1.00(±0.03) |
| HKII | 1.50(±0.13) | 1.54(±0.18) | 1.41(±0.14) | 1.36(±0.11) | 1.91(±0.13) | 1.41(±0.14) |
Data for results shown only as representative blots. The table shows protein content in skeletal muscle (SkM) in non-exercised mice as well as 6h or 10h after 2h of treadmill running in d IL-6 MKO and Control mice. Values are mean ± SE; (n = 9–10).
*: significantly different from non-exercised within given genotype (p<0.05).