Table 5.
| Non-exercised | 6h | 10h | ||||
|---|---|---|---|---|---|---|
| Liver | Control | IL-6 MKO | Control | IL-6 MKO | Control | IL-6 MKO |
| AMPKThr172 | 0.72(±0.09) | 0.62(±0.05) | 0.71(±0.07) | 0.56(±0.05) | 0.65(±0.07) | 0.61(±0.08) |
| AMPK | 0.98(±0.22) | 0.76(±0.10) | 0.72(±0.10) | 0.60(±0.07) | 0.57(±0.06) | 0.57(±0.09) |
| ACC1Ser79 | 0.94(±0.06) | 0.86(±0.04) | 0.87(±0.03) | 0.95(±0.04) | 0.94(±0.03) | 0.83(±0.03) |
| ACCSer212 | 1.15(±0.04) | 1.25(±0.05) | 1.21(±0.05) | 1.32(±0.06) | 1.30(±0.06) | 1.17(±0.06) |
| ACC1 | 0.90(±0.08) | 0.83(±0.08) | 0.86(±0.05) | 1.02(±0.07) | 1.09(±0.09) | 0.94(±0.11) |
| ACC2 | 0.73(±0.07) | 0.97(±0.1) | 0.91(±0.06) | 1.00(±0.15) | 0.90(±0.06) | 0.82(±0.11) |
| PDK4 | 1.10(±0.21) | 0.87(±0.97) | 0.96(±0.14) | 1.42(±0.27) | 0.81(±0.14) | 0.69(±0.13) |
| PDHSer300 | 1.52(±0.15) | 1.36(±0.15) | 1.44(±0.16) | 1.66(±0.11) | 1.07(±0.16)* | 1.08(±0.07)(*) |
| PDH | 1.07(±0.12) | 0.93(±0.14) | 0.94(±0.14) | 0.92(±0.08) | 1.13(±0.06) | 0.97(±0.09) |
| AMPKThr172 | 0.72(±0.09) | 0.62(±0.05) | 0.71(±0.07) | 0.56(±0.05) | 0.65(±0.07) | 0.61(±0.08) |
Data for results shown only as representative blots. The table shows protein content in liver in non-exercised mice as well as 6h or 10h after 2h of treadmill running in d IL-6 MKO and Control mice. Values are mean ± SE; (n = 9–10).
*: significantly different from non-exercised within given genotype (p<0.05).