Table 1.

Named compounds that were active in the C. elegans growth screen. Log₂-fold change in growth estimate compared to DMSO-only controls. Hit ID is as in Fig. 7B. EC₅₀ confidence interval is the standard error. The EC₅₀ estimate for mebendazole is from Fig. 3. Primary and secondary screens used solutions supplied as part of the Pathogen Box Library. EC₅₀ estimates were determined using solid material.

Compound	MMV ID	PubChem CID	Hit ID	Log2 fold change in growth		EC50 (μM) ± standard error
				(1° screen)	(2° screen)	(solid material)
Tolfenpyrad	MMV688934	10,110,536	1	−10.9	−10.6	0.2 ± 0.04
Auranofin	MMV688978	24,199,313	2	−10.9	−7.2	1.1 ± 0.3
Mebendazole	MMV003152	4030	5	−6.0	−5.7	1.1 ± 0.2
Isradipine	MMV001493	158,617	16	−2.2	−1.4	1.6 ± 0.7
Tavaborole	n/a	11,499,245		n/a	n/a	8.6 ± 1.9