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. 2017 Dec 5;17:691–703. doi: 10.1016/j.nicl.2017.12.004

Table 2.

Regions where connectivity with the amygdala changed during positive memory recall following rtfMRI-nf.

(a) Regions that showed a Group × Time interaction reflecting a differential change between groups.

(b) Regions that showed a Group × Time interaction but either showed differential baseline activity between or changed similarly in both groups.

Areaa r values
Coordinatesb Cluster size F value Pre-rtfMRI-nf
Post-rtfMRI-nf
rtfMRI-nf-induced change
Amygdala Parietal Amygdala Parietal Amygdala Parietal
a)
R inferior frontal G/lateral orbital C/BA47 35, 29, − 8 33 7.46 0.01 (0.19) 0.03 (0.22) 0.23 (0.13) 0.06 (0.12) 0.23 (0.16)# 0.03 (0.13)
L medial PFC/BA9 − 3, 53, 22 63 9.77 0.02 (0.19) 0.16 (0.22) 0.26 (0.10) 0.10 (0.05) 0.24 (0.19)# − 0.06 (0.15)
R medial PFC 13, 57, 22 61 14.0 − 0.003 (0.18) 0.10 (0.14) 0.24 (0.16) 0.08 (0.14) 0.24 (0.17)# − 0.03 (0.15)
L medial frontopolar C/BA10 − 1, 63, − 6 34 9.37 − 0.03 (0.16) − 0.01 (0.08) 0.25 (0.16) 0.05 (0.11) 0.27 (0.16)# 0.06 (0.10)
R ventrolateral PFC/BA10 43, 49, 4 65 7.46 0.06 (0.23) 0.09 (0.19) 0.17 (0.15) − 0.02 (0.18) 0.11 (0.16)# − 0.11 (0.18)
R medial frontal G 3, 27, 34 214 16.8 0.05 (0.07) 0.07 (0.16) 0.18 (0.07) 0.08 (0.10) 0.13 (0.07)# 0.02 (0.09)
R dACC 9, 5, 32 34 24.8 0.09 (0.16) 0.11 (0.10) 0.26 (0.16) 0.13 (0.09) 0.17 (0.16)# 0.02 (0.09)
R mid insula 35, − 7, 22 45 19.3 0.01 (0.18) 0.04 (0.14) 0.21 (0.06) 0.12 (0.04) 0.21 (0.12)# 0.08 (0.14)
L ventral striatum − 27, − 3, − 4 47 9.95 0.01 (0.20) 0.09 (0.13) 0.24 (0.13) 0.14 (0.08) 0.23 (0.15)# 0.04 (0.08)
R putamen 23, 3, 12 33 10.1 − 0.005 (0.21) 0.07 (0.17) 0.23 (0.09) 0.14 (0.14) 0.24 (0.18)# 0.07 (0.11)
L thalamus − 17, − 23, 10 37 19.3 0.01 (0.17) 0.06 (0.11) 0.24 (0.11) 0.10 (0.10) 0.24 (0.13)# 0.03 (0.05)
R thalamus 11, − 21, 0 36 13.4 0.08 (0.20) 0.14 (0.10) 0.32 (0.11) 0.14 (0.15) 0.24 (0.16)# 0.01 (0.17)
L precuneus − 5, − 71, 22 34 20.1 0.02 (0.21) 0.12 (0.25) 0.23 (0.06) 0.04 (0.09) 0.22 (0.18)# − 0.08 (0.19)
R precuneus 1, − 52, 56 39 18.9 0.09 (0.18) 0.16 (0.14) 0.32 (0.13) 0.14 (0.16) 0.22 (0.15)# − 0.02 (0.19)
R cerebellum 35, − 43, − 32 32 10.9 − 0.03 (0.20) 0.01 (0.15) 0.23 (0.08) 0.08 (0.13) 0.26 (0.12)# 0.07 (0.11)
R temporal pole − 43, 4, − 18 40 13.7 0.09 (0.18) 0.09 (0.19) − 0.22 (0.17) 0.09 (0.15) − 0.31 (0.18)# − 0.01 (0.25)



b)
R caudate 17, − 13, 22 39 20.1 − 0.05 (0.16) − 0.04 (0.16) 0.19 (0.06) 0.10 (0.17) 0.23 (0.14)# 0.14 (0.15)#
R dorsolateral PFC/BA6 39, 3, 46 148 31.2 0.22 (0.12) 0.05 (0.13) 0.17 (0.11) 0.12 (0.11) − 0.05 (0.21) 0.07 (0.20)#
L precentral G/BA6 − 45, − 3, 26 43 10.7 0.13 (0.09) 0.24 (0.16) 0.004 (0.18) 0.12 (0.10) − 0.13 (0.15)# − 0.12 (0.15)
L PCC − 5, − 25, 28 31 8.30 0.23 (0.12) 0.03 (0.22) − 0.05 (0.13) 0.07 (0.21) − 0.27 (0.17)# 0.04 (0.12)
R lingual G 15, − 75, − 2 33 16.5 0.27 (0.11) 0.02 (0.14) 0.02 (0.22) 0.02 (0.19) − 0.26 (0.25)# 0.01 (0.22)

Abbreviations: BA = Brodmann area; c = cortex; dACC = dorsal anterior cingulate cortex; G = gyrus; L = left; PCC = posterior cingulate cortex; PFC = prefrontal cortex; R = right.

a

Area refers to the anatomical location of the peak voxel, according to AFNI's whereami function.

b

Coordinates correspond to the stereotaxic array by Talairach and Tournoux and are listed as x, y, z, with each designating mm from the anterior commissure, such that positive x = left, positive y = anterior, and positive z = dorsal.

Significant difference from the amygdala group at p < 0.05.

#

Significant change from the Pre rtfMRI-nf Baseline at p < 0.05.