Table 3.
Regions where connectivity with the amygdala changed during rest following rtfMRI-nf.
(a) Regions that showed a Group × Time interaction reflecting a differential change between groups.
(b) Regions that showed a Group × Time interaction but either showed differential baseline activity between or changed similarly in both groups.
| Areaa | r values |
||||||||
|---|---|---|---|---|---|---|---|---|---|
| Coordinatesb | Cluster size | F value | Pre-rtfMRI-nf |
Post-rtfMRI-nf |
rtfMRI-nf-induced change |
||||
| Amygdala | Parietal | Amygdala | Parietal | Amygdala | Parietal | ||||
| a) | |||||||||
| R middle frontal G | 25, 38, 37 | 58 | 8.03 | 0.01 (0.02) | − 0.001 (0.01) | 0.13 (0.10) | − 0.004 (0.01)⁎ | 0.13 (0.10)# | 0.01 (0.01)⁎ |
| L dACC | − 3, 20, 32 | 46 | 6.45 | 0.01 (0.04) | − 0.01 (0.02) | 0.13 (0.03) | − 0.01 (0.02)⁎ | 0.09 (0.05)# | 0.003 (0.02)⁎ |
| R PCC | 1, − 48, 28 | 47 | 7.37 | 0.02 (0.05) | − 0.001 (0.05) | 0.09 (0.02) | 0.01 (0.02)⁎ | 0.07 (0.05)# | 0.01 (0.06)⁎ |
| R thalamus | 15, − 24, 0 | 32 | 6.18 | − 0.004 (0.01) | − 0.01 (0.02) | 0.08 (0.02) | − 0.01 (0.04)⁎ | 0.08 (0.07)# | 0.003 (0.04)⁎ |
| L precuneus | − 27, − 55, 41 | 72 | 6.87 | − 0.002 (0.01) | − 0.02 (0.04) | 0.09 (0.03) | 0.01 (0.04)⁎ | 0.11 (0.06)# | 0.01 (0.04)⁎ |
| R precuneus | 11, − 34, 46 | 43 | 5.83 | − 0.02 (0.03) | − 0.01 (0.02) | 0.07 (0.12) | − 0.002 (0.02)⁎ | 0.08 (0.02)# | 0.01 (0.02)⁎ |
| R PHG | 27, − 25, − 19 | 65 | 5.56 | 0.01 (0.03) | 0.04 (0.07) | 0.17 (0.10) | 0.06 (0.04)⁎ | 0.16 (0.10)# | 0.02 (0.06)⁎ |
| R hippocampus | 27, − 26, 0 | 49 | 7.17 | − 0.02 (0.05) | − 0.004 (0.01) | 0.06 (0.05) | 0.006 (0.03)⁎ | 0.09 (0.06)# | 0.01 (0.03)⁎ |
| L temporal pole/BA 38 | − 41, 3, − 18 | 75 | 6.58 | 0.06 (0.05) | 0.07 (0.05) | − 0.10 (0.04) | 0.02 (0.03)⁎ | − 0.15 (0.10)# | − 0.03 (0.06)⁎ |
| R temporal pole/BA 38 | 41, 17, − 21 | 135 | 10.1 | 0.07 (0.04) | 0.06 (0.05) | − 0.09 (0.03) | 0.02 (0.05)⁎ | − 0.16 (0.10)# | − 0.03 (0.07)⁎ |
| b) | |||||||||
| L PHG | − 25, − 4, − 14 | 92 | 9.05 | 0.01 (0.01) | − 0.004 (0.01)⁎ | 0.10 (0.14) | 0.03 (0.09) | 0.11 (0.08)# | 0.02 (0.08)⁎ |
| L insula | − 36, 18, 9 | 37 | 9.12 | − 0.002 (0.01) | − 0.02 (0.03)⁎ | 0.09 (0.05) | 0.02 (0.02)⁎ | 0.11 (0.06)# | 0.02 (0.06)⁎ |
| L middle frontal G | − 29, 10, 44 | 38 | 6.58 | 0.02 (0.04) | 0.01 (0.01) | 0.05 (0.07) | − 0.001 (0.03)⁎ | 0.04 (0.01) | − 0.001 (0.03)⁎ |
Abbreviations: BA = Brodmann area; dACC = dorsal anterior cingulate cortex; G = gyrus; L = left; PCC = posterior cingulate cortex; R = right.
Area refers to the anatomical location of the peak voxel, according to AFNI's whereami function.
Coordinates correspond to the stereotaxic array by Talairach and Tournoux.
Significant difference from the amygdala group at p < 0.05.
Significant change from the Pre rtfMRI-nf Baseline at p < 0.05.