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. Author manuscript; available in PMC: 2017 Dec 18.
Published in final edited form as: J Int Neuropsychol Soc. 2016 Feb;22(2):120–137. doi: 10.1017/S1355617715000740

Fig. 1.

Fig. 1

(a) This diagram depicts unconstrained molecular movement of a water droplet when there are no membranes to hold the water within. (b) Vertically oriented axon with a membrane wall that constrains the direction of movement of intracellular water as it moves in the same vertical direction (see up-and-down arrows) as the constraining membrane. However, as shown in (c), if the membrane breaks down or is degraded, water molecules disperse in a similar manner to the unconstrained condition. FA = fractional anisotropy, ADC = apparent diffusion coefficient, MD = mean diffusivity. Figure was created by Geri R. Hanten, Ph.D., Baylor College of Medicine.