. Author manuscript; available in PMC: 2017 Dec 18.

Published in final edited form as: Crit Rev Clin Lab Sci. 2011 Jun 24;48(2):49–70. doi: 10.3109/10408363.2011.586171

Table 1.

List of genes in the UPS reported to be regulated in skeletal muscle wasting (examples of references in parentheses).

Ubiquitin genes	Ubiquitin conjugating enzymes	Ubiquitin ligases	Deubiquitinating enzymes	Proteasome subunits
UbB (93, 200–201)	E2_14k/HR6B/UBC2 (46, 202)	MAFbx/Atrogin-1 (58, 60)	USP14 (44)	Psma1 (39, 208–209)
UbC (93, 200–201)	E2_20k (203) UBC4/UBC5 (44, 204)	MuRF-1 (58)	USP19 (55)	Psma2 (200, 210–211)
UBA52 (44)		Cbl-b (76)		Psma3 (39, 47, 200)
Ub S27A (44)		E4 (44)		Psma4 (39, 46, 209)
		E3α/UBR1 (205–206)		Psma5 (44)
		E3α-II/UBR2 UBR3 (77, 207)		Psmb1 (200, 212)
				Psmb2 (212–213)
				Psmb3 (44)
				Psmb4 (44)
				Psmc1 (51)
				Psmc2 (214–215)
				Psmc4 (51)
				Psmc5 (48) (51)
				Psmd1 (48, 51)
				Psmd3 (48)
				Psmd4 (51)
				Psmd8 (51) (44)
				Psmd11 (44)
				Psme1 (48)
				Psme3 (48)