REAGENT or RESOURCE	SOURCE	IDENTIFIER
Antibodies
Anti-IL-10 APC antibody (clone JES5-16E3)	eBioscience	clone JES5-16E3, RRID: AB_469502
Mouse IgG2k isotype control (Rat, clone A95-1)	BD Pharmingen	clone A95-1, Cat# 556924
Anti-mTLR2-IgG (clone C9A12) monoclonal antibody	InvivoGen	clone C9A12, Cat# mabg-mtlr2
Mouse IgG2A isotype control (clone 20102)	Biotechne (R&D systems)	clone 20102, MAB003
CD11b (clone M1/70)	BioLegend, London, UK	clone M1/70 RRID: AB_312791
CD11c (clone N418)	BioLegend, London, UK	clone N418 RRID: AB_313771
MHCII (clone M5/114.15.2)	BioLegend, London, UK	clone M5/114.15.2, RRID: AB_313321
CD64 (clone X54-5/7.1)	BioLegend, London, UK	clone X54-5/7.1 RRID:AB_10612740
CD45 (clone 30-F11)	BD Biosciences, Oxford, UK	clone 30-F11
Total ERK1/2	Cell Signaling Technology	#4695
pT202/Y204-ERK1/2 (clone D13.14.4E)	Cell Signaling Technology	clone D13.14.4E, #4370
Total p38	Cell Signaling Technology	#9212
pT180/Y182-p38 (clone 3D7)	Cell Signaling Technology	clone 3D7, #9215
pS133-CREB1 (clone 87G3)	Cell Signaling Technology	clone 87G3, #9198
pT581-MSK1	Cell Signaling Technology	#9595
Total CREB1 (clone E306)	Abcam	clone E306, #ab32515
Total MSK1 (#AF2518)	R&D systems	Accession #O75582
Bacterial and Virus Strains
Helicobacter hepaticus strain ATCC51449	ATCC	ATCC51449
Helicobacter hepaticus strain ATCC51448	ATCC	ATCC51448
Biological Samples
Pam2CSK4	InvivoGen	Cat# tlrl-pm2s-1
Pam3CSK4	InvivoGen	Cat# tlrl-pms
FSL-1	InvivoGen	Cat# tlrl-fsl
Zymosan, cell wall from Saccharomyces cerevisiae	InvivoGen	Cat# tlrl-zyn
LM-MS, Lipomannan from Mycobacterium smegmatis	InvivoGen	Cat# tlrl-lmms1
LPS ultrapure from E. coli O111:B4	InvivoGen	Cat# tlrl-3pelps
LPS standard from E. coli O55:B5	InvivoGen	Cat# tlrl-b5lps
Chemicals, Peptides, and Recombinant Proteins
Sodium metaperiodate	Alfa Aesar, Heysham, UK	CAS# 7790-28-5
Concanavalin A from Canavalia ensiformis (Jack bean), agarose conjugate	Sigma	L7555
Lectin from Arachis hypogaea (peanut) agarose conjugate	Sigma	L2507
Lectin from Lens culinaris (lentil), agarose conjugate	Sigma	L4018
U0126	Merck Chemicals	662005-1MG
p38 MAP Kinase Inhibitor VIII, EO 1428	Merck Chemicals	506163-5MG
NF-kB Activation Inhibitor II, JSH-23	Merck Chemicals	481408-5MG
(5Z)-7-Oxozeaenol	Calbiochem	499610
sp600125	Sigma	S5567
Critical Commercial Assays
DuoSet ELISA kits	R&D Systems Europe – Biotechne	N/A
High-Capacity cDNA Reverse Transcriptase	Applied Biosystems, Life Technologies, Paisley, UK	N/A
PrecisionFAST mastermix	Primerdesign	N/A
TaqMan gene expression assays	Life Technologies	N/A
RNeasy Mini kit (for tissue and microarray)	QIAGEN, Manchester, UK	N/A
Quick-RNA MiniPrep kit (for primary cell cultures)	Zymo Research, Cambridge Bioscience, UK	N/A
Illumina MouseWG-6-V2 microarrays	Illumina	N/A
Deposited Data
Microarray data	ArrayExpress	E-MTAB-5780
Experimental Models: Organisms/Strains
Mus musculus, NCBI Taxonomy ID:10090, C57BL/6	Charles River	RRID:IMSR_JAX:000664
Oligonucleotides
Hprt	TaqMan Gene Expression Assays for mouse, Life Technologies	Mm01545399_m1
Il10	TaqMan Gene Expression Assays for mouse, Life Technologies	Mm00439614_m1
Il6	TaqMan Gene Expression Assays for mouse, Life Technologies	Mm00446190_m1
Tnf	TaqMan Gene Expression Assays for mouse, Life Technologies	Mm00443258_m1
Fosb	TaqMan Gene Expression Assays for mouse, Life Technologies	Mm00500401_m1
Egr3	TaqMan Gene Expression Assays for mouse, Life Technologies	Mm00516979_m1
Rcan1	TaqMan Gene Expression Assays for mouse, Life Technologies	Mm01213406_m1
Cd40	TaqMan Gene Expression Assays for mouse, Life Technologies	Mm00441891_m1
Icam1	TaqMan Gene Expression Assays for mouse, Life Technologies	Mm00516023_m1
Ccl5	TaqMan Gene Expression Assays for mouse, Life Technologies	Mm01302427_m1
Software and Algorithms
FlowJo software	Tree Star, Ashland, OR	N/A
GraphPad Prism 7.02	GraphPad Software, CA	N/A
Lumi	R/Bioconductor	N/A
LIMMA	R/Bioconductor	N/A
Molecular Signatures Database (MSigDB, C3, motif gene sets)	http://software.broadinstitute.org/gsea/msigdb/collections.jsp	N/A
Transfac identifier	http://www.gene-regulation.com/pub/databases.html	N/A
runGO.py from the Computational Genomics Analysis Toolkit (CGAT)	https://github.com/CGATOxford/cgat	N/A
Other
Fortessa	BD Biosciences	N/A
ViiA 7 Real-Time PCR System	Life Technologies	N/A