1 contraindicated medical conditions include past history of breast cancer, endometrial cancer or ovarian cancer.
2numbers don't add up to 45,663 due to the time varying nature of hysterectomy status: 903 change from no hysterectomy to hysterectomy and are counted in both cells
3 vaginal estrogen cream or vaginal tablet at some time during follow-up (Estradiol ring was only ascertained during the Extension Study; users are not included in this analysis)