Table 2.
Relative risk (95% CI) of anastomotic dehiscence, infection, and death in eleven randomised trials of early enteral nutrition
| Anastomotic dehiscence | Infections
|
Vomiting | Death | ||||
|---|---|---|---|---|---|---|---|
| Any infection | Wound infection | Pneumonia | Intra-abdominal abscess | ||||
| Sagar et al20 | 0.33 (0.01 to 7.58) | 0.71 (0.29 to 1.75) | 0.60 (0.17 to 2.07) | NR | 1.00 (0.16 to 6.20) | NR | NR |
| Schroeder et al13 | NR | 3.00 (0.13 to 68.6) | NR | 3.00 (0.13 to 68.6) | NR | NR | NR |
| Binderow et al21 | NR | NR | NR | NR | NR | 1.75 (0.85 to 3.56) | NR |
| Reissman et al22 | 0.34 (0.01 to 8.16) | 1.27 (0.35 to 4.54) | 2.02 (0.19 to 21.9) | 0.34 (0.01 to 8.16) | 1.01 (0.06 to 15.9) | 1.56 (0.78 to 3.13) | NR |
| Carr et al23 | NR | 0.14 (0.01 to 2.53) | NR | NR | NR | NR | 0.33 (0.01 to 7.54) |
| Beier-Holgersen et al24 | 0.50 (0.10 to 2.53) | 0.14 (0.04 to 0.57 | 0.10 (0.01 to 0.73) | 0.5 (0.05 to 5.22) | 0.20 (0.01 to 4.00) | 0.88 (0.55 to 1.42) | 0.50 (0.01 to 2.53) |
| Ortiz et al25 | 0.50 (0.09 to 2.67) | 0.80 (0.33 to 1.94) | 0.83 (0.26 to 2.64) | 1.00 (0.14 to 6.95) | 1.00 (0.06 to 15.8) | NR | NR |
| Heslin et al26 | 0.76 (0.17 to 3.30) | 0.95 (0.62 to 1.44) | 1.64 (0.71 to 3.78) | 0.43 (0.12 to 1.63) | 2.02 (0.19 to 21.9) | 1.38 (0.86 to 2.21) | 0.67 (0.12 to 3.94) |
| Hartsell et al27 | 0.33 (0.01 to 7.86) | 3.00 (0.13 to 70.7) | NR | 3.00 (0.13 to 70.7) | NR | 1.40 (0.75 to 2.62) | 0.33 (0.01 to 7.86) |
| Watters et al28 | 0.27 (0.03 to 2.12) | NR | NR | NR | NR | NR | NR |
| Stewart et al29 | 3.00 (0.16 to 71.5) | 0.56 (0.20 to 1.51) | 0.11 (0.01 to 2.00) | 1.00 (0.06 to 15.4) | NR | 1.00 (0.55 to 1.82) | 0.33 (0.01 to 7.95) |
| Combined relative risk | 0.53 (0.26 to 1.08) | 0.72 (0.54 to 0.98) | 0.71 (0.44 to 1.17) | 0.73 (0.33 to 1.59) | 0.87 (0.31 to 2.42) | 1.27 (1.01 to 1.61) | 0.48 (0.18 to 1.29) |
| P value from test for heterogeneity | 0.96 | 0.22 | 0.074 | 0.85 | 0.84 | 0.52 | 0.99 |
NR=not reported or no events occurred.