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. 2017 Dec 18;7:17737. doi: 10.1038/s41598-017-18175-3

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© The Author(s) 2017

Open Access This article is licensed under a Creative Commons Attribution 4.0 International License, which permits use, sharing, adaptation, distribution and reproduction in any medium or format, as long as you give appropriate credit to the original author(s) and the source, provide a link to the Creative Commons license, and indicate if changes were made. The images or other third party material in this article are included in the article’s Creative Commons license, unless indicated otherwise in a credit line to the material. If material is not included in the article’s Creative Commons license and your intended use is not permitted by statutory regulation or exceeds the permitted use, you will need to obtain permission directly from the copyright holder. To view a copy of this license, visit http://creativecommons.org/licenses/by/4.0/.

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Differential expression miR-21 in fibrotic and non-fibrotic tubules. The region of fibrotic and non-fibrotic tubules in the kidneys of mice treated with deoxycorticosterone acetate (DOCA)-salt for 8 days or the controls was collected using laser capture microdissection (LCM). (A) Representative images of kidney sections before and after LCM. (B) The levels of mRNA-21 expression in fibrotic and non-fibrotic tubules in the mice treated with DOCA-salt and tubules in the controls were measured, and 18 s rRNA is used as internal control. *P < 0.05 compared to the controls, n = 3, error bars represent mean ± SD.