Table 3.

Fixed effect coefficients (b) and 95% confidence intervals (bootstrapped-based p-values) for the association between sickness behaviour and inflammatory markers

	Time-pts	Obs	b	CI	b womena	CI
FENOb	5	494	0.04	−0.02; 0.09	−0.07	−0.17; 0.03
Perennial IgEb	2	308	0.13	−0.08; 0.34	−0.21	−0.45; 0.03
Seasonal IgEb	2	308	−0.06	−0.15; 0.03	−0.16	−0.34; 0.01
Food IgEb	2	308	−0.07	−0.35; 0.21	−0.03	−0.35; 0.28
Total IgEb	2	326	−0.15	−0.06; 0.36	−0.07	−0.34; 0.19
S-ECP	2	308	0.15	−0.01; 0.31	−0.13	−0.35; 0.10
P-EDN	2	308	−0.05	−0.17; 0.07	−0.12	−0.71; 0.48

BMI body mass index, Time-pts number of time points included in analysis, obs number of observations included in analysis, CI confidence intervals, F _E NO exhaled fraction of nitric oxide, S-ECP serum eosinophil cationic protein, P-EDN plasma eosinophil-derived neurotoxin

Note: Fixed effect coefficients (b) and 95% confidence intervals for the association between sickness behaviour vs. F_ENO, IgE, S-ECP and P-EDN. All analyses were adjusted for BMI and age

^a Interaction term between independent variable and sex (woman = 1)

^b All IgE, S-ECP and P-EDN values were z-transformed to facilitate interpretation of regression coefficients