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. 2017 Dec 14;8:922. doi: 10.3389/fphar.2017.00922

Table 3.

Antithrombotic efficiencies of aptamer RA-36 and bivalirudin: mean area of thrombus at the beginning and at the end of the observation.

Group Mean area of thrombus, mm2
The first 5 min The last 5 min
Control 0.26 ± 0.09 0.62 ± 0.18
Bivalirudin 0.19 mg/kg 0.27 ± 0.09 0.38 ± 0.17
Bivalirudin 0.38 mg/kg 0.22 ± 0.10 0.39 ± 0.15
Bivalirudin 0.75 mg/kg 0.17 ± 0.07 0.28 ± 0.18
Aptamer RA-36 7.0 mg/kg 0.21 ± 0.07 0.5 ± 0.2
Aptamer RA-36 35 mg/kg 0.12 ± 0.12 0.3 ± 0.3
Aptamer RA-36 70 mg/kg 0.10 ± 0.09 0.15 ± 0.16