Table 2.
Immunohistochemical Investigation
| Uniprot Acc. | Protein Name | Gene Name | Ø FC | P Value | CI.L | CI.R | Ø Identified Peptides | Ø Sequence Coverage [%] | |
|---|---|---|---|---|---|---|---|---|---|
| Recurrent LNM vs TU with LNM | Q9UGV2 | Protein NDRG3 | NDRG3 | 1.43 | .00029 | 0.88 | 1.98 | 2.60 | 9.79 |
| P09874 | Poly-(ADP-Ribose)-Polymerase | PARP1 | 0.63 | .0361 | 0.05 | 1.22 | 6.20 | 8.42 | |
| Q8NFV4 | Alpha/beta hydrolase domain-containing protein 11 | ABHD11 | 2.30 | .0021 | 1.02 | 3.59 | 2.8 | 9.3 | |
| Q8TE77 | Protein phosphatase Slingshot homolog 3 | SSH3 | 1.77 | .0026 | 0.85 | 2.69 | 0.7 | 1.4 | |
| TU with LNM vs TU without LNM | Q8TC12 | Retinol dehydrogenase 11 | RDH11 | 1.23 | .00361 | 0.48 | 1.97 | 8.33 | 33.07 |
Proteins chosen for immunohistochemical corroboration are listed with their respective FC value, P value, confidence intervals, average number of identified peptides, as well as average sequence coverage among the five biological replicates per group. The FC value is the log2-transformed ratio of a protein's intensity in two samples, which is commonly calculated to show an increase (for positive values) or decrease (for negative values) of the respective proteins' abundance in one condition/sample.