Table 1.
Subject characteristics.
| untrained or trained (n = 52) | Untrained (n = 24) | trained (n = 28) | p-value | ||||
|---|---|---|---|---|---|---|---|
| Age (years) | 28.1 ± 0.9 | (19.0–38.0) | 26.3 ± 1.14 | (19.0–37.4) | 28.1 ± 1.2 | (19.0–38.0) | 0.2605 |
| Mass (kg) | 77.6 ± 1.6 | (58.3–99.0) | 77.7 ± 2.41 | (59.7–99.0) | 79.9 ± 2.4 | (58.3–99.0) | 0.5194 |
| Height (cm) | 180.3 ± 1.6 | (155.7–204.4) | 180.9 ± 2.72 | (158.4–204.4) | 181.7 ± 0.0 | (1.6–2.0) | 0.8391 |
| BMI (kg m−2) | 23.9 ± 0.5 | (18.5–30.9) | 24.0 ± 0.73 | (18.5–30.9) | 24.1 ± 0.7 | (19.4–29.6) | 0.9330 |
| Body fat (%) | 17.3 ± 1.1 | (6.0–32.1) | 22.2 ± 6.92 | (10.7–32.1) | 14.2 ± 1.3 | (6.0–28.0) | 0.0030 |
| Fat-free- mass (kg) | 64.6 ± 1.3 | (48.5–79.6) | 59.8 ± 1.6 | (48.5–71.6) | 64.6 ± 1.2 | (58.7–79.6) | 0.0004 |
| Systolic BP (mm Hg) | 123.8 ± 1.6 | (104.9–148.0) | 124.0 ± 2.27 | (104.9–134.3) | 125.3 ± 2.2 | (113.1–148.0) | 0.6785 |
| Diastolic BP (mm Hg) | 74.3 ± 1.3 | (62.3–92.0) | 74.0 ± 2.10 | (63.7–83.5) | 75.3 ± 2.0 | (62.3–92.0) | 0.6664 |
| PPO (Watt) | 315.8 ± 8.4 | (229.5–467.5) | 293.4 ± 11.35 | (229.5–387.6) | 361.1 ± 11.6 | (252.0–467.5) | 0.0001 |
| O2peak (mL O2 min−1) | 4107.5 ± 102.3 | (2983.5–5816.8) | 3815.7 ± 148.89 | (2983.5–5102.9) | 4589.3 ± 152.4 | (3315.0–5816.8) | 0.0008 |
| O2peakr (mL O2 min−1 kg−1) | 53.8 ± 1.2 | (38.7–72.7) | 48.8 ± 1.70 | (38.7–61.4) | 59.5 ± 1.7 | (49.9–72.7) | 0.0001 |
| RERrest (CO2/ O2) | 0.77 ± 0.01 | (0.58–0.99) | 0.77 ± 0.02 | (0.58–0.99) | 0.72 ± 0.03 | (0.63–0.89) | 0.2156 |
| RERpeak (CO2/ O2) | 1.11 ± 0.02 | (0.84–1.32) | 1.10 ± 0.03 | (0.84–1.32) | 1.07 ± 0.19 | (0.97–1.30) | 0.6640 |
Values represent mean ± SE of values (minima-maxima) of the studied subjects combined (n = 52) and split for endurance training status (trained n = 28; untrained n = 24). P-values refer to the significance of differences between the trained and untrained group (univariate ANOVA for ACE-I/D allele × training status as a factor). Underlined p-values denote those differences, which passed the threshold of a false discovery rate of 5%. BMI, body mass index; BP, blood pressure; PPO, peak power output (during two-legged exercise); RERpeak, peak respiration exchange ratio during two-legged exercise; RERrest, respiration exchange ratio at rest before two-legged exercise; O2peak, peak oxygen uptake (during two-legged exercise); O2peakr, body mass-related peak oxygen uptake during two-legged exercise.