Table 5.
Response by irAE and Disease Type
| Best Response | mM | mRCC | ||
|---|---|---|---|---|
| irAE, n = 84 | No irAE, n = 539 | irAE, n = 46 | No irAE, n = 873 | |
| Complete Response (CR) | 5(6.0%) | 23(4.3%) | 3 (6.5%) | 44(5.0%) |
| Partial Response (PR) | 27 (32.1%) | 89 (16.5%) | 10 (21.7%) | 153 (17.5%) |
| Stable Disease (SD) | 29 (34.5%) | 167 (31.0%) | 19 (41.3%) | 317 (36.3%) |
| Progressive Disease (PD) | 19 (22.6%) | 211 (39.1%) | 13 (28.3%) | 262 (30.0%) |
| Missing | 4 (4.8%) | 49 (9.1%) | 1 (2.2%) | 97 (11.1%) |
| CR + PR (n,%) | 32 (38.1%) | 112 (20.8%) aP = 0.0058 |
13 (28.3%) | 197 (22.6%) aP = 0.5999 |
| CR + PR+ SD (n, %) | 61 (72.6%) | 279 (51.8%) bP = 0.0013 |
32 (69.6%) | 514 (58.9%) bP = 0.6263 |
aFisher’s exact test comparing best response by irAE
bFisher’s exact test comparing tumor control by irAE