Fig. 2.

LR agonist activity of patient-derived autologous DRibbles. HEKBlue reporter cell lines (TLR2, TLR3, TLR4, TLR7, TLR9, NOD2 and control cell line Null1) were incubated with 20ìl autologous DRibbles (Patient 2, Patient 3, Patient 5, Patient 6) (in triplicate) for 16 hrs. SEAP secretion in the media was measured in Quanti-Blue media by absorbance at 600nm and compared to cell line specific positive controls